产品详情
所在位置: 首页> 产品目录> A类> abbexa>
查看大图

  • 产品名称：ACK1 (pY518) Antibody

  • 产品型号：abx032041
  • 产品厂商：abbexa
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
ACK1 (pY518) Antibody
详情介绍：
ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP) stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.

Target ACK1 (pY518)
Clonality Polyclonal
Target Modification Tyr518
Modification Phosphorylation
Reactivity Human
Tested Applications ELISA, DB
Host Rabbit
Recommended dilutions DB: 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y518 of human ACK1.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q07912 (UniProt, ExPASy)
UniProt Secondary AC Q6ZMQ0, Q8N6U7, Q96H59
UniProt Entry Name ACK1_HUMAN
KEGG hsa:10188
String 9606.ENSP00000371341
Molecular Weight Calculated MW: 115 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Cow TNK2.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on ACK1 (pY518)
姓名：
电话：
您的需求：
 

沪公网安备 31011002002624号