产品详情
简单介绍:
AP-3 Complex Subunit Mu-1 (AP3M1) Antibody
详情介绍:
The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane and may be directly involved in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternatively spliced transcript variants encoding the same protein have been observed.
Research Articles on AP-3 Complex Subunit Mu-1 (AP3M1)
| Target | AP-3 Complex Subunit Mu-1 (AP3M1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 390-418 amino acids from the C-terminal region of human AP3M1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9Y2T2 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5JQ12, Q9H5L2 |
| UniProt Entry Name | AP3M1_HUMAN |
| Gene Symbol | AP3M1 |
| String | 9606.ENSP00000347408 |
| Molecular Weight | Calculated MW: 46.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Cow AP3M1. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
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