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  • 产品名称:AP-3 Complex Subunit Mu-1 (AP3M1) Antibody

  • 产品型号:abx029928
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简单介绍:
AP-3 Complex Subunit Mu-1 (AP3M1) Antibody
详情介绍:
The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane and may be directly involved in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternatively spliced transcript variants encoding the same protein have been observed.

Target AP-3 Complex Subunit Mu-1 (AP3M1)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 390-418 amino acids from the C-terminal region of human AP3M1.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9Y2T2 (UniProt, ExPASy)
UniProt Secondary AC Q5JQ12, Q9H5L2
UniProt Entry Name AP3M1_HUMAN
Gene Symbol AP3M1
String 9606.ENSP00000347408
Molecular Weight Calculated MW: 46.9 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Mouse and Cow AP3M1.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on AP-3 Complex Subunit Mu-1 (AP3M1)
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