产品名称：ATP Synthase Subunit Alpha, Mitochondrial (ATP5F1A) Antibody

ATP Synthase Subunit Alpha, Mitochondrial (ATP5F1A) Antibody is a Rabbit Polyclonal antibody for the detection of ATP5A1.

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the alpha subunit of the catalytic core. Alternatively spliced transcript variants encoding the different isoforms have been identified. Pseudogenes of this gene are located on chromosomes 9, 2, and 16.

Target	ATP Synthase Subunit Alpha, Mitochondrial (ATP5F1A)
Clonality	Polyclonal
Reactivity	Human, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P25705 (UniProt, ExPASy)
UniProt Entry Name	ATPA_HUMAN
Gene Symbol	ATP5F1A
GeneID	498
OMIM	164360
HGNC	823
KEGG	hsa:498
Ensembl	ENSG00000152234
String	9606.ENSP00000381736
Enzyme Commission Number	EC 3.6.3.14
Molecular Weight	Observed MW: 54 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on ATP Synthase Subunit Alpha, Mitochondrial (ATP5F1A)