产品名称：ATP synthase subunit a (MT-ATP6) Antibody

ATP synthase subunit a (MT-ATP6) Antibody is a Rabbit Polyclonal antibody for the detection of MT-ATP6.

Mitochondrial membrane ATP synthase (F (1F (0 ATP synthase or Complex V produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F (1 - containing the extramembraneous catalytic core and F (0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F (1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.

Target	ATP synthase subunit a (MT-ATP6)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	ATP synthase subunit a
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P00846 (UniProt, ExPASy)
UniProt Entry Name	ATP6_HUMAN
Gene Symbol	MT-ATP6
GeneID	4508
HGNC	7414
KEGG	hsa:4508
Molecular Weight	Observed MW: 25 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on ATP synthase subunit a (MT-ATP6)