产品名称：ATP-Dependent 6-Phosphofructokinase, Muscle Type (PFKM) Antibody

PFKM Antibody is a Rabbit Polyclonal antibody against PFKM. Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.

Target	ATP-Dependent 6-Phosphofructokinase, Muscle Type (PFKM)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 501-780 of human PFKM.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P08237 (UniProt, ExPASy)
UniProt Secondary AC	J3KNX3, Q16814, Q16815, Q6ZTT1
Gene Symbol	PFKM
GeneID	5213
NCBI Accession	NP_001160160.1
Molecular Weight	Calculated MW: 85 kDa Observed MW: 85 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on ATP-Dependent 6-Phosphofructokinase, Muscle Type (PFKM)