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  • 产品名称：Activated CDC42 Kinase 1 (ACK1) Antibody

  • 产品型号：abx033628
  • 产品厂商：abbexa
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简单介绍：
Activated CDC42 Kinase 1 (ACK1) Antibody
详情介绍：
ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP) stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.

Target Activated CDC42 Kinase 1 (ACK1)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 934-964 amino acids from the C-terminal region of human ACK1.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q07912 (UniProt, ExPASy)
UniProt Secondary AC Q6ZMQ0, Q8N6U7, Q96H59
UniProt Entry Name ACK1_HUMAN
NCBI Accession NP_001010938.1 NP_005772.3
KEGG hsa:10188
String 9606.ENSP00000371341
Molecular Weight Calculated MW: 115 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Cow TNK2.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Activated CDC42 Kinase 1 (ACK1)
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