产品名称：Activating Transcription Factor 7-Interacting Protein 2 (ATF7IP2) Antibody

ATF7IP2/MCAF2 is a recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable).

Target	Activating Transcription Factor 7-Interacting Protein 2 (ATF7IP2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 318-347 amino acids from the central region of human MCAF2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q5U623 (UniProt, ExPASy)
UniProt Secondary AC	B2RNR2, Q53EZ7, Q658U2, Q6IS97, Q8N9X8, Q9H9L6
UniProt Entry Name	MCAF2_HUMAN
KEGG	hsa:80063
String	9606.ENSP00000379808
Molecular Weight	Calculated MW: 75.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Activating Transcription Factor 7-Interacting Protein 2 (ATF7IP2)