产品详情
简单介绍:
Adenine Phosphoribosyltransferase (APRT) Antibody
详情介绍:
A conserved feature of APRT is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2, 8-dihydroxyadenine urolithiasis.
Research Articles on Adenine Phosphoribosyltransferase (APRT)
Target | Adenine Phosphoribosyltransferase (APRT) |
Clonality | Polyclonal |
Reactivity | Human |
Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
Host | Rabbit |
Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Immunogen | KLH-conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human APRT. |
Isotype | IgG |
Form | Liquid |
Purification | Purified through a protein A column, followed by peptide affinity purification. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
UniProt Primary AC | P07741 (UniProt, ExPASy) |
UniProt Secondary AC | G5E9J2, Q3KP55, Q68DF9 |
UniProt Entry Name | APT_HUMAN |
NCBI Accession | NP_000476.1 NP_001025189.1 |
KEGG | hsa:353 |
String | 9606.ENSP00000367615 |
Molecular Weight | Calculated MW: 19.6 kDa |
Buffer | PBS containing 0.09% sodium azide. |
Availability | Shipped within 5-10 working days. |
Note | This product is for research use only. |
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