产品名称：Actin, Alpha Skeletal Muscle (ACTA1) Antibody

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

Target	Actin, Alpha Skeletal Muscle (ACTA1)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Mouse
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Human ACTA1 recombinant protein.
Isotype	IgG1 Kappa
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P68133 (UniProt, ExPASy)
UniProt Secondary AC	P02568, P99020, Q5T8M9
UniProt Entry Name	ACTS_HUMAN
KEGG	hsa:58
String	9606.ENSP00000355645
Molecular Weight	Calculated MW: 42.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat, Cow, Pig, Chicken and Rabbit ACTA1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Actin, Alpha Skeletal Muscle (ACTA1)