产品名称：Activin A Receptor Type 1B (ACVR1B) Antibody

This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.

Target	Activin A Receptor Type 1B (ACVR1B)
Clonality	Monoclonal
Reactivity	Mouse
Tested Applications	ELISA, WB
Host	Mouse
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Human ACVR1B recombinant protein.
Isotype	IgG1 Kappa
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P36896 (UniProt, ExPASy)
UniProt Secondary AC	B7Z5L8, B7Z5W5, Q15479, Q15480, Q15481, Q15482
UniProt Entry Name	ACV1B_HUMAN
KEGG	hsa:91
String	9606.ENSP00000442656
Molecular Weight	Calculated MW: 56.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Activin A Receptor Type 1B (ACVR1B)