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  • 产品名称：Aldose Reductase (AKR1B1) Antibody

  • 产品型号：abx031674
  • 产品厂商：abbexa
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简单介绍：
Aldose Reductase (AKR1B1) Antibody
详情介绍：
AKR1B1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol.

Target Aldose Reductase (AKR1B1)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 102-135 amino acids from the Central region of human AKR1B1.
Isotype IgG
Form Liquid
Purification Purified Rabbit Polyclonal Antibody.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P15121 (UniProt, ExPASy)
UniProt Secondary AC B2R8N3, Q5U031, Q6FGA4, Q6ICP2, Q9BS21, Q9UCI9
UniProt Entry Name ALDR_HUMAN
Gene Symbol AKR1B1
GeneID 231
OMIM 103880
NCBI Accession NP_001619.1
HGNC 381
KEGG hsa:231
Ensembl ENSG00000085662
String 9606.ENSP00000285930
Enzyme Commission Number EC 1.1.1.21
Molecular Weight Calculated MW: 35.9 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Aldose Reductase (AKR1B1)
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