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  • 产品名称：ABHD2 Positive Control for STJ500017 peptide (STJ505473)

  • 产品型号：STJ505473-5
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
ABHD2 Positive Control for STJ500017 peptide (STJ505473)
详情介绍：
Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: ABHD2 Positive Control for STJ500017 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Abhd2
Gene ID: 54608
Uniprot ID: ABHD2_MOUSE
Specificity: This is positive control is recommended for use in combination with ABHD2 antibody STJ500017.
Tissue Specificity Widely expressed with higher expression in testis. Expressed by vascular smooth muscle cells, non vascular smooth muscle cells and heart.
Function Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation. Involved in acrosomal reaction (Probable). May also play a role in smooth muscle cells migration.
Peptide Name Monoacylglycerol Lipase Abhd2
2-Arachidonoylglycerol Hydrolase
Abhydrolase Domain-Containing Protein 2
Acetylesterase
Lung Alpha/Beta Hydrolase 2
Mmlabh2
Triacylglycerol Lipase
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Cytoplasmic Vesicle
Secretory Vesicle
Acrosome Membrane
Absent From The Sperm Flagellum
Alternative Peptide Names Monoacylglycerol Lipase Abhd2 protein
2-Arachidonoylglycerol Hydrolase protein
Abhydrolase Domain-Containing Protein 2 protein
Acetylesterase protein
Lung Alpha/Beta Hydrolase 2 protein
Mmlabh2 protein
Triacylglycerol Lipase protein
Abhd2 protein
Labh-2 protein
Labh2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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