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  • 产品名称：Aquaporin 2 Blocking Peptide peptide (STJ503662)

  • 产品型号：STJ503662-250
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Aquaporin 2 Blocking Peptide peptide (STJ503662)
详情介绍：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Aquaporin 2 Blocking Peptide is synthetically produced from the 200-250 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Aqp2
Gene ID: 25386
Uniprot ID: AQP2_RAT
Immunogen Region: 200-250
Immunogen: Synthetic peptide taken within amino acid region 200-250 on human Aquaporin 2 protein.
Tissue Specificity Detected in kidney, in cortical and the medullary collecting tubules (at protein level). Detected in kidney medulla and cortex.
Post Translational Modifications Ser-256 phosphorylation is necessary and sufficient for expression at the apical membrane. Endocytosis is not phosphorylation-dependent. N-glycosylated.
Function Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential role in renal water homeostasis.
Peptide Name Aquaporin-2
Aqp-2
Adh Water Channel
Aquaporin-Cd
Aqp-Cd
Collecting Duct Water Channel Protein
Wch-Cd
Water Channel Protein For Renal Collecting Duct
Database Links Reactome: R-RNO-432040
Reactome: -RNO-432047
Cellular Localisation Apical Cell Membrane
Multi-Pass Membrane Protein
Basolateral Cell Membrane
Cell Membrane
Cytoplasmic Vesicle Membrane
Golgi Apparatus
Trans-Golgi Network Membrane
Shuttles From Vesicles To The Apical Membrane
Vasopressin-Regulated Phosphorylation Is Required For Translocation To The Apical Cell Membrane
Plekha8/Fapp2 Is Required To Transport Aqp2 From The Tgn To Sites Where Aqp2 Is Phosphorylated
Alternative Peptide Names Aquaporin-2 protein
Aqp-2 protein
Adh Water Channel protein
Aquaporin-Cd protein
Aqp-Cd protein
Collecting Duct Water Channel Protein protein
Wch-Cd protein
Water Channel Protein For Renal Collecting Duct protein
Aqp2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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