产品详情
简单介绍:
Aquaporin 3 Blocking Peptide peptide (STJ503663)
详情介绍:
Applications: | Immunodepletion/Immunocompetition |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Aquaporin 3 Blocking Peptide is synthetically produced from the 200-250 sequence and is suitable for use in western blot applications. |
Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | Aqp3 |
Gene ID: | 65133 |
Uniprot ID: | AQP3_RAT |
Immunogen Region: | 200-250 |
Immunogen: | Synthetic peptide taken within amino acid region 200-250 on rat Aquaporin 3 protein. |
Tissue Specificity | Detected in kidney medulla and papilla, in collecting duct cells. Detected in colon. |
Function | Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism. |
Peptide Name | Aquaporin-3 Aqp-3 31.4 Kda Water Channel Protein Aquaglyceroporin-3 |
Database Links | Reactome: R-RNO-432040 Reactome: -RNO-432047 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Basolateral Cell Membrane |
Alternative Peptide Names | Aquaporin-3 protein Aqp-3 protein 31.4 Kda Water Channel Protein protein Aquaglyceroporin-3 protein Aqp3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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