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  • 产品名称：ASNA1 Positive Control for STJ500179 peptide (STJ503704)

  • 产品型号：STJ503704-5
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
ASNA1 Positive Control for STJ500179 peptide (STJ503704)
详情介绍：
Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: ASNA1 Positive Control for STJ500179 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: GET3
Gene ID: 439
Uniprot ID: GET3_HUMAN
Specificity: This is positive control is recommended for use in combination with ASNA1 antibody STJ500179.
Tissue Specificity Expressed in the epithelial cells of the liver, kidney, and stomach wall, in the adrenal medulla, in the islet cells of the pancreas, in the red pulp of the spleen, and in cardiac and skeletal muscle.
Function ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1/WRB and CAMLG/GET2, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the GET1-CAMLG receptor, and returning it to the cytosol to initiate a new round of targeting. May be involved in insulin signaling.
Peptide Name Atpase Get3
Arsenical Pump-Driving Atpase
Arsenite-Stimulated Atpase
Guided Entry Of Tail-Anchored Proteins Factor 3 - Atpase
Transmembrane Domain Recognition Complex 40 Kda Atpase Subunit
Harsa-I
Hasna-I
Database Links Reactome: R-HSA-9609523
Cellular Localisation Cytoplasm
Endoplasmic Reticulum
Nucleus
Nucleolus
Alternative Peptide Names Atpase Get3 protein
Arsenical Pump-Driving Atpase protein
Arsenite-Stimulated Atpase protein
Guided Entry Of Tail-Anchored Proteins Factor 3 - Atpase protein
Transmembrane Domain Recognition Complex 40 Kda Atpase Subunit protein
Harsa-I protein
Hasna-I protein
GET3 protein
ARSA protein
ASNA1 protein
TRC40 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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