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  • 产品名称：Anti-ABHD2 antibody (200-250) {FITC} (STJ500017)

  • 产品型号：STJ500017-100
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ABHD2 antibody (200-250) {FITC} (STJ500017)
详情介绍：
Host: Rabbit
Applications: ELISA/IHC/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ABHD2 (200-250) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: FITC
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5 µg/µl
Dilution Range: WB: 1:500
ELISA: 1:10, 000
IP: 1:150
IHC: 1:50-1:150
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Abhd2
Gene ID: 54608
Uniprot ID: ABHD2_MOUSE
Immunogen Region: 200-250
Immunogen: Synthetic peptide taken within amino acid region 200-250 on mouse a/b hydrolase II protein.
Tissue Specificity Widely expressed with higher expression in testis. Expressed by vascular smooth muscle cells, non vascular smooth muscle cells and heart.
Function Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation. Involved in acrosomal reaction (Probable). May also play a role in smooth muscle cells migration.
Protein Name Monoacylglycerol Lipase Abhd2
2-Arachidonoylglycerol Hydrolase
Abhydrolase Domain-Containing Protein 2
Acetylesterase
Lung Alpha/Beta Hydrolase 2
Mmlabh2
Triacylglycerol Lipase
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Cytoplasmic Vesicle
Secretory Vesicle
Acrosome Membrane
Absent From The Sperm Flagellum
Alternative Antibody Names Anti-Monoacylglycerol Lipase Abhd2 antibody
Anti-2-Arachidonoylglycerol Hydrolase antibody
Anti-Abhydrolase Domain-Containing Protein 2 antibody
Anti-Acetylesterase antibody
Anti-Lung Alpha/Beta Hydrolase 2 antibody
Anti-Mmlabh2 antibody
Anti-Triacylglycerol Lipase antibody
Anti-Abhd2 antibody
Anti-Labh-2 antibody
Anti-Labh2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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