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  • 产品名称：CACNB2 Blocking Peptide peptide (Phospho) (STJ504581)

  • 产品型号：STJ504581-250
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
CACNB2 Blocking Peptide peptide (Phospho) (STJ504581)
详情介绍：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Phospho-CACNB2 Blocking Peptide is synthetically produced from the 600-655 sequence and is suitable for use in western blot applications.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Cacnb2
Gene ID: 116600
Uniprot ID: CACB2_RAT
Immunogen Region: 600-655
Immunogen: Synthetic peptide taken within amino acid region 600-655 on rat CACNB2 protein.
Tissue Specificity Highly expressed in heart and brain, and at lower levels in lung.
Post Translational Modifications Regulated through phosphorylation at Thr-549 by CaMK2D.
Function Beta subunit of voltage-dependent calcium channels which contributes to the function of the calcium channel by increasing peak calcium current. Plays a role in shifting voltage dependencies of activation and inactivation of the channel. May modulate G protein inhibition. May contribute to beta-adrenergic augmentation of Ca(2+) influx in cardiomyocytes, thereby regulating increases in heart rate and contractile force. Involved in membrane targeting of the alpha-1 subunit CACNA1C.
Peptide Name Voltage-Dependent L-Type Calcium Channel Subunit Beta-2
Cab2
Calcium Channel Voltage-Dependent Subunit Beta 2
Database Links Reactome: R-RNO-112308
Reactome: -RNO-422356
Reactome: -RNO-5576892
Reactome: -RNO-5576893
Cellular Localisation Cell Membrane
Sarcolemma
Peripheral Membrane Protein
Cytoplasmic Side
Alternative Peptide Names Voltage-Dependent L-Type Calcium Channel Subunit Beta-2 protein
Cab2 protein
Calcium Channel Voltage-Dependent Subunit Beta 2 protein
Cacnb2 protein
Cacnlb2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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