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  • 产品名称：Anti-ACAA2 antibody (298-397) [S4MR] (STJ11102704)

  • 产品型号：STJ11102704
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ACAA2 antibody (298-397) [S4MR] (STJ11102704)
详情介绍：
Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-ACAA2 (298-397) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: S4MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ACAA2
Gene ID: 10449
Uniprot ID: THIM_HUMAN
Immunogen Region: 298-397
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 298-397 of human ACAA2 (P42765).
Immunogen Sequence: PAISGALKKAGLSLKDMDLV EVNEAFAPQYLAVERSLDLD ISKTNVNGGAIALGHPLGGS GSRITAHLVHELRRRGGKYA VGSACIGGGQGIAVIIQSTA
Function In the production of energy from fats, this is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA (Probable). Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain unbranched 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms (Probable). Also catalyzes the condensation of two acetyl-CoA molecules into acetoacetyl-CoA and could be involved in the production of ketone bodies (Probable). Also displays hydrolase activity on various fatty acyl-CoAs. Thereby, could be responsible for the production of acetate in a side reaction to beta-oxidation (Probable). Abolishes BNIP3-mediated apoptosis and mitochondrial damage.
Protein Name 3-Ketoacyl-Coa Thiolase - Mitochondrial
Acetyl-Coa Acetyltransferase
Acetyl-Coa Acyltransferase
Acyl-Coa Hydrolase - Mitochondrial
Beta-Ketothiolase
Mitochondrial 3-Oxoacyl-Coa Thiolase
T1
Database Links Reactome: R-HSA-77289
Cellular Localisation Mitochondrion
Alternative Antibody Names Anti-3-Ketoacyl-Coa Thiolase - Mitochondrial antibody
Anti-Acetyl-Coa Acetyltransferase antibody
Anti-Acetyl-Coa Acyltransferase antibody
Anti-Acyl-Coa Hydrolase - Mitochondrial antibody
Anti-Beta-Ketothiolase antibody
Anti-Mitochondrial 3-Oxoacyl-Coa Thiolase antibody
Anti-T1 antibody
Anti-ACAA2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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