产品详情
简单介绍:
Human BTN3A1/CD277 protein (Recombinant) (C-hFc & His) (STJP002694)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human BTN3A1/CD277-C-hFc & His protein was developed from hek293 cells and has a target region of C-hFc & His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Immunoreactivity: | Measured by its ability to inhibit Anti-CD3-induced proliferation of jurkat. The ED50 for this effect is 24-96 ng/mL. |
Gene Symbol: | BTN3A1 |
Gene ID: | 11119 |
Uniprot ID: | BT3A1_HUMAN |
Immunogen Region: | Gln30-Gly254 |
Immunogen: | Recombinant human BTN3A1/CD277 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Gln30-Gly254) of human BTN3A1/CD277 (Accession #NP_919423.1) fused with an Fc, 6×His tag at the C-terminus. |
Post Translational Modifications | N-glycosylated. |
Function | Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate. |
Protein Name | Butyrophilin Subfamily 3 Member A1 Cd Antigen Cd277 |
Database Links | Reactome: R-HSA-8851680 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative Protein Names | Butyrophilin Subfamily 3 Member A1 protein Cd Antigen Cd277 protein BTN3A1 protein BTF5 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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