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  • 产品名称：Anti-Acetyl-E2F2-Lys122 antibody (STJA0005927)

  • 产品型号：STJA0005927
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-Acetyl-E2F2-Lys122 antibody (STJA0005927)
详情介绍：
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Acetyl-Transcription factor E2F2-Lys122 is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: E2F2
Gene ID: 1870
Uniprot ID: E2F2_HUMAN
Specificity: This antibody detects endogenous levels of Human, Mouse E2F-2 (Acetyl Lys122)
Immunogen: Synthesized peptide derived from human E2F-2 (Acetyl Lys122)
Tissue Specificity Highest level of expression is found in placenta, low levels are found in lung. Found as well in many immortalized cell lines derived from tumor samples.
Post Translational Modifications Phosphorylated by CDK2 and cyclin A-CDK2 in the S-phase.
Function Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTCCGCGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F2 binds specifically to RB1 in a cell-cycle dependent manner.
Protein Name Transcription Factor E2f2
E2f-2
Database Links Reactome: R-HSA-2559580
Reactome: R-HSA-2559585
Reactome: R-HSA-69231
Reactome: R-HSA-9661069
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Transcription Factor E2f2 antibody
Anti-E2f-2 antibody
Anti-E2F2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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