产品详情
简单介绍:
Human CD20 protein (Recombinant) (STJP000412)
详情介绍:
Host: | HEK293 |
Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human CD20-protein was developed from hek293. For use in research applications. |
Conjugation: | Unconjugated |
Formulation: | 0.2 Mu m filtered PBS solution, pH7.2. |
Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Gene Symbol: | MS4A1 |
Gene ID: | 931 |
Uniprot ID: | CD20_HUMAN |
Immunogen Region: | Cytoplasmic domain |
Immunogen: | Optimized DNA sequence encoding cytoplasmic domain of human CD20 including a N-terminal 6His tag was expressed in HEK293 cells. NA |
Tissue Specificity | Expressed on B-cells. |
Post Translational Modifications | Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate. |
Function | B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. |
Protein Name | B-Lymphocyte Antigen Cd20 B-Lymphocyte Surface Antigen B1 Bp35 Leukocyte Surface Antigen Leu-16 Membrane-Spanning 4-Domains Subfamily A Member 1 Cd Antigen Cd20 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Lipid-Anchor Constitutively Associated With Membrane Rafts |
Alternative Protein Names | B-Lymphocyte Antigen Cd20 protein B-Lymphocyte Surface Antigen B1 protein Bp35 protein Leukocyte Surface Antigen Leu-16 protein Membrane-Spanning 4-Domains Subfamily A Member 1 protein Cd Antigen Cd20 protein MS4A1 protein CD20 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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