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  • 产品名称：Human CD208 (LAMP3) protein (Recombinant) (STJP000708)

  • 产品型号：STJP000708
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human CD208 (LAMP3) protein (Recombinant) (STJP000708)
详情介绍：
Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human CD208 (LAMP3)-protein was developed from hek293. For use in research applications.
Conjugation: Unconjugated
Formulation: 0.2 Mu m filtered PBS solution, pH7.2.
Storage Instruction: Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Gene Symbol: LAMP3
Gene ID: 27074
Uniprot ID: LAMP3_HUMAN
Immunogen Region: ECD
Immunogen: Optimized DNA sequence encoding Human extracellular domain of human CD208including a C-terminal 6His tag was expressed in HEK293 cells. NA
Tissue Specificity Detected in tonsil interdigitating dendritic cells, in spleen, lymph node, Peyer's patches in the small instestine, in thymus medulla and in B-cells (at protein level). Expressed in lymphoid organs and dendritic cells. Expressed in lung. Up-regulated in carcinomas of the esophagus, colon, rectum, ureter, stomach, breast, fallopian tube, thyroid and parotid tissues.
Function Lysosomal membrane glycoprotein which plays a role in the unfolded protein response (UPR) that contributes to protein degradation and cell survival during proteasomal dysfunction. Plays a role in the process of fusion of the lysosome with the autophagosome, thereby modulating the autophagic process. Promotes hepatocellular lipogenesis through activation of the PI3K/Akt pathway. May also play a role in dendritic cell function and in adaptive immunity. (Microbial infection) Plays a positive role in post-entry steps of influenza A virus replication, either virus uncoating, cytosolic transport, or nuclear import of viral components, and promotes nuclear accumulation of influenza nucleoprotein/NP at early stages of viral infection. (Microbial infection) Supports the FURIN-mediated cleavage of mumps virus fusion protein F by interacting with both FURIN and the unprocessed form but not the processed form of the viral protein F. (Microbial infection) Promotes the intracellular proliferation of Salmonella typhimuium.
Protein Name Lysosome-Associated Membrane Glycoprotein 3
Lamp-3
Lysosomal-Associated Membrane Protein 3
Dc-Lysosome-Associated Membrane Glycoprotein
Dc Lamp
Protein Tsc403
Cd Antigen Cd208
Cellular Localisation Cell Surface
Lysosome Membrane
Single-Pass Type I Membrane Protein
Cytoplasmic Vesicle Membrane
Early Endosome Membrane
During Dendritic Cell Maturation
Detected On Cytoplasmic Vesicles (The Mhc Ii Compartment) That Contain Mhc Ii Proteins
Lamp1
Lamp2 And Lamp3
Detected On Lysosomes In Mature Dendritic Cells
Alternative Protein Names Lysosome-Associated Membrane Glycoprotein 3 protein
Lamp-3 protein
Lysosomal-Associated Membrane Protein 3 protein
Dc-Lysosome-Associated Membrane Glycoprotein
Dc Lamp protein
Protein Tsc403 protein
Cd Antigen Cd208 protein
LAMP3 protein
DCLAMP protein
TSC403 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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