产品详情
简单介绍:
Human Chitinase-1/CHIT1 protein (Recombinant) (C-His) (STJP001019)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human Chitinase-1/CHIT1-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
Immunoreactivity: | Measured by its ability to cleave 4-Methylumbelliferyl-beta-D-N, N NA, N”-triacetylchitotriose (4-MU-TACT). The specific activity is >43571 pmol/min/Mu g. |
Gene Symbol: | CHIT1 |
Gene ID: | 1118 |
Uniprot ID: | CHIT1_HUMAN |
Immunogen: | Recombinant Human Chitinase-1/CHIT1 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ala22-Asn466) of human CHIT1 (Accession #NP_003456) fused with a 6×His tag at the C-terminus. |
Tissue Specificity | Detected in spleen. Secreted by cultured macrophages. |
Function | Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity. |
Protein Name | Chitotriosidase-1 Chitinase-1 |
Database Links | Reactome: R-HSA-189085 Reactome: R-HSA-6798695 |
Cellular Localisation | Secreted Lysosome A Small Proportion Is Lysosomal |
Alternative Protein Names | Chitotriosidase-1 protein Chitinase-1 protein CHIT1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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