产品详情
简单介绍:
Human CLEC12A/MICL/CLL-1 protein (Recombinant) (N-His, C-Avi) {Biotin} (STJP001721)
详情介绍:
Host: | HEK293 |
Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human CLEC12A/MICL/CLL-1-N-His, C-Avi protein was developed from hek293 and has a target region of N-His, C-Avi. For use in research applications. |
Conjugation: | Biotin |
Formulation: | Lyophilised from 0.2 µm filtered PBS solution pH7.4. |
Dilution Range: | Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM |
Storage Instruction: | The lyophilized protein is stable for at least 1 year from date of receipt at-20°C. |
Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). |
Gene Symbol: | CLEC12A |
Gene ID: | 160364 |
Uniprot ID: | CL12A_HUMAN |
Immunogen Region: | His65-Ala265 |
Immunogen: | DNA sequence encoding Human CLEC12A/MICL/CLL-1 including a N-His, C-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology. |
Post Translational Modifications | Highly N-glycosylated. Glycosylation varies between cell types. |
Function | Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. |
Protein Name | C-Type Lectin Domain Family 12 Member A C-Type Lectin-Like Molecule 1 Cll-1 Dendritic Cell-Associated Lectin 2 Dcal-2 Myeloid Inhibitory C-Type Lectin-Like Receptor Micl Cd Antigen Cd371 |
Database Links | Reactome: R-HSA-6798695 |
Cellular Localisation | Cell Membrane Single-Pass Type Ii Membrane Protein Ligand Binding Leads To Internalization |
Alternative Protein Names | C-Type Lectin Domain Family 12 Member A protein C-Type Lectin-Like Molecule 1 protein Cll-1 protein Dendritic Cell-Associated Lectin 2 protein Dcal-2 protein Myeloid Inhibitory C-Type Lectin-Like Receptor protein Micl protein Cd Antigen Cd371 protein CLEC12A protein CLL1 protein DCAL2 protein MICL protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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