产品详情
简单介绍:
Human CNTFR-alpha protein (Recombinant) (C-His) (STJP001011)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human CNTFR-alpha-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human CNTFR at 3 Mu g/mL (100 Mu L/well) can bind Recombinant Human CNTF with a linear range of 0.078-6.3 Mu g/mL. |
Gene Symbol: | CNTFR |
Gene ID: | 1271 |
Uniprot ID: | CNTFR_HUMAN |
Immunogen Region: | Gln 23-Pro 346 |
Immunogen: | Recombinant Human CNTFR-alpha Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln 23-Pro 346 ) of human CNTF R alpha (Accession #NP_001833.1) fused with a 6×His tag at the C-terminus. |
Tissue Specificity | Nervous system and skeletal muscle. |
Function | Binds to CNTF. The alpha subunit provides the receptor specificity. Receptor for heterodimeric neurotropic cytokine composed of CLCF1/CLC and CRLF1/CLF-1. Acts as a receptor for the neuroprotective peptide humanin as part of a complex with IL6ST/GP130 and IL27RA/WSX1. |
Protein Name | Ciliary Neurotrophic Factor Receptor Subunit Alpha Cntf Receptor Subunit Alpha Cntfr-Alpha |
Database Links | Reactome: R-HSA-6788467 |
Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor |
Alternative Protein Names | Ciliary Neurotrophic Factor Receptor Subunit Alpha protein Cntf Receptor Subunit Alpha protein Cntfr-Alpha protein CNTFR protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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