产品详情
简单介绍:
Human Coagulation factor III/CD142 protein (Recombinant) (C-His) (STJP000888)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human Coagulation factor III/CD142-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation. |
Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilized Human CD142 at 1 Mu g/mL (100 Mu L/well) can bind Human Tissue Factor Rabbit mAb with a linear range of 0.98-61.71 ng/mL.2. Measured by its ability to activate Coagulation Factor VII |
Gene Symbol: | F3 |
Gene ID: | 2152 |
Uniprot ID: | TF_HUMAN |
Immunogen: | Recombinant Human Coagulation factor III/CD142 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly34-Glu251) of human Coagulation Factor III/Tissue Factor/CD142 (Accession #NP_001984.1) fused with |
Tissue Specificity | Lung, placenta and pancreas. |
Function | Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The TF:VIIa complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. |
Protein Name | Tissue Factor Tf Coagulation Factor Iii Thromboplastin Cd Antigen Cd142 |
Database Links | Reactome: R-HSA-140834 Reactome: R-HSA-9031628 |
Cellular Localisation | Isoform 1: Membrane Single-Pass Type I Membrane Protein Isoform 2: Secreted |
Alternative Protein Names | Tissue Factor protein Tf protein Coagulation Factor Iii protein Thromboplastin protein Cd Antigen Cd142 protein F3 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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