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  • 产品名称：Cytokeratin 20 Blocking Peptide peptide (STJ503850)

  • 产品型号：STJ503850-250
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Cytokeratin 20 Blocking Peptide peptide (STJ503850)
详情介绍：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Cytokeratin 20 Blocking Peptide is synthetically produced from the 300-350 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: KRT20
Gene ID: 54474
Uniprot ID: K1C20_HUMAN
Immunogen Region: 300-350
Immunogen: Synthetic peptide taken within amino acid region 300-350 human keratin, type I cytoskeletal 20 protein.
Tissue Specificity Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa.specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa.
Post Translational Modifications Hyperphosphorylation at Ser-13 occurs during the early stages of apoptosis but becomes less prominent during the later stages. Phosphorylation at Ser-13 also increases in response to stress brought on by cell injury. Proteolytically cleaved by caspases during apoptosis. Cleavage occurs at Asp-228.
Function Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine.
Peptide Name Keratin - Type I Cytoskeletal 20
Cytokeratin-20
Ck-20
Keratin-20
K20
Protein It
Database Links Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Cellular Localisation Cytoplasm
Alternative Peptide Names Keratin - Type I Cytoskeletal 20 protein
Cytokeratin-20 protein
Ck-20 protein
Keratin-20 protein
K20 protein
Protein It protein
KRT20 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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