产品详情
简单介绍:
Human DPEP1 protein (Recombinant) (C-His) (STJP002700)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human DPEP1-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications. |
Formulation: | Lyophilized from a 0.22 Mu m filtered solution of 20mM PB, 150mM NaCl, pH7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DPEP1 |
Gene ID: | 1800 |
Uniprot ID: | DPEP1_HUMAN |
Immunogen Region: | Asp17-Ser385 |
Immunogen: | Recombinant Human DPEP1 Protein is produced by Mammalian expression system. The target protein is expressed with sequence (Asp17-Ser385) of human Dipeptidase 1 (Accession #P16444) fused with a 6×His tag at the C-terminus. |
Function | Hydrolyzes a wide range of dipeptides including the conversion of leukotriene D4 to leukotriene E4. Hydrolyzes cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation. Possesses also beta lactamase activity and can hydrolyze the beta-lactam antibiotic imipenem. Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver. |
Protein Name | Dipeptidase 1 Beta-Lactamase Dehydropeptidase-I Microsomal Dipeptidase Renal Dipeptidase Hrdp |
Database Links | Reactome: R-HSA-2142691 Reactome: R-HSA-5423646 Reactome: R-HSA-9664535 |
Cellular Localisation | Apical Cell Membrane Lipid-Anchor Gpi-Anchor Cell Projection Microvillus Membrane Brush Border Membrane |
Alternative Protein Names | Dipeptidase 1 protein Beta-Lactamase protein Dehydropeptidase-I protein Microsomal Dipeptidase protein Renal Dipeptidase protein Hrdp protein DPEP1 protein MDP protein RDP protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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