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  • 产品名称：Human Fc-gamma RIIa/CD32a (H167R) protein (Recombinant) (C-His) (STJP000857)

  • 产品型号：STJP000857
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human Fc-gamma RIIa/CD32a (H167R) protein (Recombinant) (C-His) (STJP000857)
详情介绍：
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Fc-gamma RIIa/CD32a (H167R)-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized recombinant human CD32a at 1 Mu g/mL (100 Mu L/well) can bind biotinylated human IgG1 with a linear range of 30-250 ng/mL.
Gene Symbol: FCGR2A
Gene ID: 2212
Uniprot ID: FCG2A_HUMAN
Immunogen: Recombinant Human Fc-gamma RIIa/CD32a (H167R) Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala36-Ile218 (R167) ) of human Fc gamma RIIA/CD32a (Accession #NP_001129691.1) fused with a 6×His tag
Tissue Specificity Found on monocytes, neutrophils and eosinophil platelets.
Post Translational Modifications Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK.
Function Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Protein Name Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A
Igg Fc Receptor Ii-A
Cdw32
Fc-Gamma Rii-A
Fc-Gamma-Riia
Fcrii-A
Cd Antigen Cd32
Database Links Reactome: R-HSA-2029481
Reactome: R-HSA-2029482
Reactome: R-HSA-2029485
Reactome: R-HSA-6798695
Reactome: R-HSA-9664323
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A protein
Igg Fc Receptor Ii-A protein
Cdw32 protein
Fc-Gamma Rii-A protein
Fc-Gamma-Riia protein
Fcrii-A protein
Cd Antigen Cd32 protein
FCGR2A protein
CD32 protein
FCG2 protein
FCGR2A1 protein
IGFR2 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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