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  • 产品名称：Human CD40 (TNFRSF5) protein (Recombinant) (STJP000492)

  • 产品型号：STJP000492
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human CD40 (TNFRSF5) protein (Recombinant) (STJP000492)
详情介绍：
Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human CD40 (TNFRSF5)-protein was developed from hek293. For use in research applications.
Conjugation: Unconjugated
Formulation: Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose.
Storage Instruction: Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Immunoreactivity: The activity was tested by the ability of immobilized recombinant human CD40 to bind Human CD40 Ligand with a linear range of 10-500 ng/ml NA
Gene Symbol: CD40
Gene ID: 958
Uniprot ID: TNR5_HUMAN
Immunogen Region: ECD
Immunogen: Optimized DNA sequence encoding extracellular domain of Human CD40 including a C-terminal His tag was expressed in HEK293 cells. NA
Tissue Specificity B-cells and in primary carcinomas.
Function Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 5
B-Cell Surface Antigen Cd40
Bp50
Cd40l Receptor
Cdw40
Cd Antigen Cd40
Database Links Reactome: R-HSA-198933 P25942-1
Reactome: R-HSA-5668541 P25942-1
Reactome: R-HSA-5676594 P25942-1
Cellular Localisation Isoform I: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform Ii: Secreted
Alternative Protein Names Tumor Necrosis Factor Receptor Superfamily Member 5 protein
B-Cell Surface Antigen Cd40 protein
Bp50 protein
Cd40l Receptor protein
Cdw40 protein
Cd Antigen Cd40 protein
CD40 protein
TNFRSF5 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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