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  • 产品名称：Human CD79B protein (Recombinant) (C-His-Avi) {Biotin} (STJP001748)

  • 产品型号：STJP001748
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human CD79B protein (Recombinant) (C-His-Avi) {Biotin} (STJP001748)
详情介绍：
Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human CD79B-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: CD79B
Gene ID: 974
Uniprot ID: CD79B_HUMAN
Immunogen Region: Ala29-Asp159
Immunogen: DNA sequence encoding Human CD79B including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Post Translational Modifications Phosphorylated on tyrosine upon B-cell activation by SRC-type Tyr-kinases such as BLK, LYN and SYK.
Function Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
Protein Name B-Cell Antigen Receptor Complex-Associated Protein Beta Chain
B-Cell-Specific Glycoprotein B29
Ig-Beta
Immunoglobulin-Associated B29 Protein
Cd Antigen Cd79b
Database Links Reactome: R-HSA-5690714
Reactome: R-HSA-9679191
Reactome: R-HSA-983695
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Following Antigen Binding
The Bcr Has Been Shown To Translocate From Detergent-Soluble Regions Of The Cell Membrane To Lipid Rafts Although Signal Transduction Through The Complex Can Also Occur Outside Lipid Rafts
Alternative Protein Names B-Cell Antigen Receptor Complex-Associated Protein Beta Chain protein
B-Cell-Specific Glycoprotein B29 protein
Ig-Beta protein
Immunoglobulin-Associated B29 Protein protein
Cd Antigen Cd79b protein
CD79B protein
B29 protein
IGB protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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