产品详情
简单介绍:
Human Cystatin A protein (Recombinant) (STJP000307)
详情介绍:
Host: | HEK293 |
Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human Cystatin A-protein was developed from hek293. For use in research applications. |
Conjugation: | Unconjugated |
Formulation: | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
Dilution Range: | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Immunoreactivity: | The activity was tested by the ability to inhibit Cathepsin L cleavage of a fluorogenic substrate. The ED50 was measured to be 10nM NA |
Gene Symbol: | CSTA |
Gene ID: | 1475 |
Uniprot ID: | CYTA_HUMAN |
Immunogen Region: | ILE 2-PHE98 |
Immunogen: | Optimized DNA sequence encoding Human Cystatin A-CSTA (ILE 2-PHE98) mature chain including a C-terminal His tag was expressed in HEK293 cells. NA |
Tissue Specificity | Expressed in the skin throughout the epidermis. |
Function | This is an intracellular thiol proteinase inhibitor. Has an important role in desmosome-mediated cell-cell adhesion in the lower levels of the epidermis. |
Protein Name | Cystatin-A Cystatin-As Stefin-A Cleaved Into - Cystatin-A - N-Terminally Processed |
Database Links | Reactome: R-HSA-6809371 |
Cellular Localisation | Cytoplasm |
Alternative Protein Names | Cystatin-A protein Cystatin-As protein Stefin-A Cleaved Into - Cystatin-A - N-Terminally Processed protein CSTA protein STF1 protein STFA protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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