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  • 产品名称：Anti-ADAM9 antibody (120-200 aa) (STJ190515)

  • 产品型号：STJ190515
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ADAM9 antibody (120-200 aa) (STJ190515)
详情介绍：
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Disintegrin and metalloproteinase domain-containing protein 9 (120-200 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ADAM9
Gene ID: 8754
Uniprot ID: ADAM9_HUMAN
Immunogen Region: 120-200 aa
Specificity: ADAM9 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from the human protein at the amino acid range 120-200
Post Translational Modifications Proteolytically cleaved in the trans-Golgi network before it reaches the plasma membrane to generate a mature protein. The removal of the pro-domain occurs via cleavage at two different sites. Processed most likely by a pro-protein convertase such as furin, at the boundary between the pro-domain and the catalytic domain. An additional upstream cleavage pro-protein convertase site (Arg-56/Glu-57) has an important role in the activation of ADAM9. Phosphorylation is induced in vitro by phorbol-12-myristate-13-acetate (PMA).
Function Metalloprotease that cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins. Isoform 2: May act as alpha-secretase for amyloid precursor protein (APP).
Protein Name Disintegrin And Metalloproteinase Domain-Containing Protein 9
Adam 9
Cellular Disintegrin-Related Protein
Meltrin-Gamma
Metalloprotease/Disintegrin/Cysteine-Rich Protein 9
Myeloma Cell Metalloproteinase
Database Links Reactome: R-HSA-1442490
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Alternative Antibody Names Anti-Disintegrin And Metalloproteinase Domain-Containing Protein 9 antibody
Anti-Adam 9 antibody
Anti-Cellular Disintegrin-Related Protein antibody
Anti-Meltrin-Gamma antibody
Anti-Metalloprotease/Disintegrin/Cysteine-Rich Protein 9 antibody
Anti-Myeloma Cell Metalloproteinase antibody
Anti-ADAM9 antibody
Anti-KIAA0021 antibody
Anti-MCMP antibody
Anti-MDC9 antibody
Anti-MLTNG antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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