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  • 产品名称：Human GHRL/MTLRP protein (Recombinant) (C-RaFC) (STJP001964)

  • 产品型号：STJP001964
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human GHRL/MTLRP protein (Recombinant) (C-RaFC) (STJP001964)
详情介绍：
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human GHRL/MTLRP-C-RaFC protein was developed from hek293 cells and has a target region of C-RaFC. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GHRL
Gene ID: 51738
Uniprot ID: GHRL_HUMAN
Immunogen Region: Gly24-Lys117
Immunogen: Recombinant Human GHRL/MTLRP Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly24-Lys117) of human GHRL/MTLRP (Accession #NP_001128413.1) fused with RaFc tag at the C-terminus.
Post Translational Modifications O-octanoylated by GOAT/MBOAT4. O-octanoylation or O-decanoylation is essential for ghrelin activity. The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28-C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26. A small fraction of ghrelin, ghrelin-28-C10:1, may be modified with a singly unsaturated carboxylic acid. Also O-acetylated and O-butyrylated on Ser-26 to minor levels. Amidation of Leu-98 is essential for obestatin activity.
Function Ghrelin-27: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. Ghrelin-28: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation. Obestatin: May be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility.
Protein Name Appetite-Regulating Hormone
Growth Hormone Secretagogue
Growth Hormone-Releasing Peptide
Motilin-Related Peptide
Protein M46 Cleaved Into - Ghrelin-27 - Ghrelin-28
Ghrelin - Obestatin
Database Links Reactome: R-HSA-375276 Q9UBU3-1
Reactome: R-HSA-416476 Q9UBU3-1
Reactome: R-HSA-422085
Cellular Localisation Secreted
Alternative Protein Names Appetite-Regulating Hormone protein
Growth Hormone Secretagogue protein
Growth Hormone-Releasing Peptide protein
Motilin-Related Peptide protein
Protein M46 Cleaved Into - Ghrelin-27 - Ghrelin-28 protein
Ghrelin - Obestatin protein
GHRL protein
MTLRP protein
UNQ524 protein
PRO1066 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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