产品详情
简单介绍:
Anti-ADAMTS9 antibody (210-290 aa) (STJ190521)
详情介绍:
Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-A disintegrin and metalloproteinase with thrombospondin motifs 9 (210-290 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ADAMTS9 |
Gene ID: | 56999 |
Uniprot ID: | ATS9_HUMAN |
Immunogen Region: | 210-290 aa |
Specificity: | ATS9 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 210-290 |
Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. N-glycosylated. Can be O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X(2)-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of ADAMTS family members. Can also be C-glycosylated with one or two mannose molecules on tryptophan residues within the consensus sequence W-X-X-W of the TPRs, and N-glycosylated. These other glycosylations can also facilitate secretion. |
Function | Cleaves the large aggregating proteoglycans, aggrecan (at the '1838-Glu-|-Ala-1839' site) and versican (at the '1428-Glu-|-Ala-1429' site). Has a protease-independent function in promoting the transport from the endoplasmic reticulum to the Golgi apparatus of a variety of secretory cargos. |
Protein Name | A Disintegrin And Metalloproteinase With Thrombospondin Motifs 9 Adam-Ts 9 Adam-Ts9 Adamts-9 |
Database Links | Reactome: R-HSA-1474228 Reactome: R-HSA-5083635 Reactome: R-HSA-5173214 |
Cellular Localisation | Secreted Extracellular Space Extracellular Matrix Endoplasmic Reticulum |
Alternative Antibody Names | Anti-A Disintegrin And Metalloproteinase With Thrombospondin Motifs 9 antibody Anti-Adam-Ts 9 antibody Anti-Adam-Ts9 antibody Anti-Adamts-9 antibody Anti-ADAMTS9 antibody Anti-KIAA1312 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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