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  • 产品名称：Human Hepatocyte Growth Factor protein (Recombinant) (STJP000426)

  • 产品型号：STJP000426
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human Hepatocyte Growth Factor protein (Recombinant) (STJP000426)
详情介绍：
Host: CHO cells
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human Hepatocyte Growth Factor-protein was developed from cho cells. For use in research applications.
Conjugation: Unconjugated
Formulation: Lyophilised from 0.2 Mu m filtered solution in 0.5% glycine, 0.5% sucrose,.01% Tween80, mM Glutamic acid, pH7.5.
Dilution Range: Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers.
Storage Instruction: Can be stored in working aliquots at°C-°C C for one month, or at-20°C C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. NA
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than.1 ng/µg (1EU/µg). NA
Immunoreactivity: The ED (50) was determined by the dose-dependent stimulation of the proliferation ofmurine BNL-CL2cell li was found to be in the range of.0-40.0 ng/ml. NA
Gene Symbol: HGF
Gene ID: 3082
Uniprot ID: HGF_HUMAN
Immunogen Region: Mature chain
Immunogen: Optimized DNA sequence encoding Human Hepatocyte Growth Factor mature chain was expressed in Chinese Hamster Ovary cell line. NA
Immunogen Sequence: MWVTKLLPAL LLQHVLLHLL LLPIAIPYAE GQRKRRNTIH EFKKSAKTTL IKIDPALKIK TKKVNTADQC ANRCTRNKGL PFTCKAFVFD KARKQCLWFP FNSMSSGVKK EFGHEFDLYE NKDYIRNCII GKGRSYKGTV SITKSGIKCQ PWSSMIPHEH SFLPSSYRGK DLQENYCRNP RGEEGGPWCF TSNPEVRYEV CDIPQCSEVE CMTCNGESYR GLMDHTES
Post Translational Modifications The single-chain precursor undergoes proteolytic processing by TMPRSS13 resulting in an active two-chain form.
Function Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Activates MAPK signaling following TMPRSS13 cleavage and activation.
Protein Name Hepatocyte Growth Factor
Hepatopoietin-A
Scatter Factor
Sf Cleaved Into - Hepatocyte Growth Factor Alpha Chain - Hepatocyte Growth Factor Beta Chain
Database Links Reactome: R-HSA-114608
Reactome: R-HSA-1257604
Reactome: R-HSA-1266695
Reactome: R-HSA-2219530
Reactome: R-HSA-5673001
Reactome: R-HSA-6785807
Reactome: R-HSA-6806942
Reactome: R-HSA-6807004
Reactome: R-HSA-6811558
Reactome: R-HSA-8851805
Reactome: R-HSA-8851907
Reactome: R-HSA-8865999
Reactome: R-HSA-8874081
Reactome: R-HSA-8875513
Reactome: R-HSA-8875555
Reactome: R-HSA-8875656
Reactome: R-HSA-8875791
Reactome: R-HSA-9734091
Alternative Protein Names Hepatocyte Growth Factor protein
Hepatopoietin-A protein
Scatter Factor protein
Sf Cleaved Into - Hepatocyte Growth Factor Alpha Chain - Hepatocyte Growth Factor Beta Chain protein
HGF protein
HPTA protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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