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  • 产品名称：Human IFN-gamma R2 protein (Recombinant) (C-RaFC) (STJP001843)

  • 产品型号：STJP001843
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human IFN-gamma R2 protein (Recombinant) (C-RaFC) (STJP001843)
详情介绍：
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human IFN-gamma R2-C-RaFC protein was developed from hek293 cells and has a target region of C-RaFC. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: IFNGR2
Gene ID: 3460
Uniprot ID: INGR2_HUMAN
Immunogen Region: Ser28-Asp240
Immunogen: Recombinant Human IFN-gamma R2 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ser28-Asp240) of human IFN-gamma R2 (Accession #NP_005525.2) fused with and a RaFc tag at the C-terminus.
Function Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activation of the JAK/STAT signaling pathway. Required for signal transduction in contrast to other receptor subunit responsible for ligand binding.
Protein Name Interferon Gamma Receptor 2
Ifn-Gamma Receptor 2
Ifn-Gamma-R2
Interferon Gamma Receptor Accessory Factor 1
Af-1
Interferon Gamma Receptor Beta-Chain
Ifn-Gamma-R-Beta
Interferon Gamma Transducer 1
Database Links Reactome: R-HSA-877300
Reactome: R-HSA-877312
Reactome: R-HSA-9679191
Reactome: R-HSA-9732724
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cytoplasmic Vesicle Membrane
Golgi Apparatus Membrane
Endoplasmic Reticulum Membrane
Cytoplasm
Has Low Cell Surface Expression And High Cytoplasmic Expression In T Cells
The Bias Towards Cytoplasmic Expression May Be Due To Ligand-Independent Receptor Internalization And Recycling
Alternative Protein Names Interferon Gamma Receptor 2 protein
Ifn-Gamma Receptor 2 protein
Ifn-Gamma-R2 protein
Interferon Gamma Receptor Accessory Factor 1 protein
Af-1 protein
Interferon Gamma Receptor Beta-Chain protein
Ifn-Gamma-R-Beta protein
Interferon Gamma Transducer 1 protein
IFNGR2 protein
IFNGT1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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