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  • 产品名称：Glucose Transporter GLUT4 Blocking Peptide peptide (STJ504144)

  • 产品型号：STJ504144-250
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Glucose Transporter GLUT4 Blocking Peptide peptide (STJ504144)
详情介绍：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Glucose Transporter GLUT4 Blocking Peptide is synthetically produced from the 450-509 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Slc2a4
Gene ID: 20528
Uniprot ID: GLUT4_MOUSE
Immunogen Region: 450-509
Immunogen: Synthetic peptide taken within amino acid region 450-509 on mouse Solute carrier family 2, facilitated glucose transporter member 4 protein.
Tissue Specificity Expressed in skeletal and cardiac muscles. Expressed in brown and white adipose tissues.
Post Translational Modifications Sumoylated. Palmitoylated. Palmitoylation by ZDHHC7 controls the insulin-dependent translocation of GLUT4 to the plasma membrane.
Function Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell.
Peptide Name Solute Carrier Family 2 - Facilitated Glucose Transporter Member 4
Gt2
Glucose Transporter Type 4 - Insulin-Responsive
Glut-4
Database Links Reactome: R-MMU-189200
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Endomembrane System
Cytoplasm
Perinuclear Region
Localizes Primarily To The Perinuclear Region
Undergoing Continued Recycling To The Plasma Membrane Where It Is Rapidly Reinternalized
The Dileucine Internalization Motif Is Critical For Intracellular Sequestration
Insulin Stimulation Induces Translocation To The Cell Membrane
Alternative Peptide Names Solute Carrier Family 2 - Facilitated Glucose Transporter Member 4 protein
Gt2 protein
Glucose Transporter Type 4 - Insulin-Responsive protein
Glut-4 protein
Slc2a4 protein
Glut4 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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