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  • 产品名称：Human ABCC10 (ATP Binding Cassette Transporter C10) Sandwich ELISA Kit (STJE0006816)

  • 产品型号：STJE0006816
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human ABCC10 (ATP Binding Cassette Transporter C10) Sandwich ELISA Kit (STJE0006816)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.061ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This ABCC10 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: ABCC10
Gene ID: 89845
Uniprot ID: MRP7_HUMAN
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity In testis, localized to peritubular myoid cells, Leydig cells, along the basal membrane of Sertoli cells, moderately in the adluminal compartment of the seminiferous tubules, and in vascular endothelial cells. Isoform 1: Specifically expressed in spleen. Isoform 2: Widely expressed.
Post Translational Modifications
Function ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Lipophilic anion transporter that mediates ATP-dependent transport of glucuronide conjugates such as estradiol-17-beta-o-glucuronide and GSH conjugates such as leukotriene C4 (LTC4). May contribute to regulate the transport of organic compounds in testes across the blood-testis-barrier (Probable). Mediates multidrug resistance (MDR) in cancer cells by preventing the intracellular accumulation of certain antitumor drugs, such as, docetaxel and paclitaxel. Does not transport glycocholic acid, taurocholic acid, MTX, folic acid, cAMP, or cGMP.
Protein Name Atp-Binding Cassette Sub-Family C Member 10
Multidrug Resistance-Associated Protein 7
Database Links Reactome: R-HSA-382556
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Basolateral Cell Membrane
Basal Cell Membrane
Localized To The Basal Membrane Of Sertoli Cells
Alternative ELISA Names Atp-Binding Cassette Sub-Family C Member 10 ELISA kit
Multidrug Resistance-Associated Protein 7 ELISA kit
ABCC10 ELISA kit
MRP7 ELISA kit
SIMRP7 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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