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  • 产品名称：GPCR LGR6 Blocking Peptide peptide (STJ504294)

  • 产品型号：STJ504294-250
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
GPCR LGR6 Blocking Peptide peptide (STJ504294)
详情介绍：
Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: GPCR LGR6 Blocking Peptide is synthetically produced from the 850-920 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: LGR6
Gene ID: 59352
Uniprot ID: LGR6_HUMAN
Immunogen Region: 850-920
Immunogen: Synthetic peptide taken within amino acid region 850-920 on human LRG6 protein.
Function Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
Peptide Name Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 6
Database Links Reactome: R-HSA-4641263
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Peptide Names Leucine-Rich Repeat-Containing G-Protein Coupled Receptor 6 protein
LGR6 protein
UNQ6427 protein
PRO21331 protein
VTS20631 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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