产品详情
简单介绍:
Anti-ADSL antibody (1-310) (STJ28200)
详情介绍:
Host: | Rabbit |
Applications: | WB/IF/IP |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-ADSL (1-310) is suitable for use in Western Blot, Immunofluorescence and Immunoprecipitation research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 IF/ICC 1:20-1:100 IP 1:50-1:100 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ADSL |
Gene ID: | 158 |
Uniprot ID: | PUR8_HUMAN |
Immunogen Region: | 1-310 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human ADSL (NP_000017.1). |
Immunogen Sequence: | MAAGGDHGSPDSYRSPLASR YASPEMCFVFSDRYKFRTWR QLWLWLAEAEQTLGLPITDE QIQEMKSNLENIDFKMAAEE EKRLRHDVMAHVHTFGHCCP KAAGIIHLGATSCYVGDNTD LIILRNALDLLLPKLARVIS RLADFAKERASLPTLGFTHF QPAQLTTVGKRCCLWIQDLC MDLQNLKRVRDDLRFRGVKG TTGTQASFLQLFEGDDHKVE QLDKMVTEKAGFKRAFIIT |
Tissue Specificity | Ubiquitously expressed. Both isoforms are produced by all tissues. Isoform 2 is 10-fold less abundant than isoform 1. |
Function | Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate. |
Protein Name | Adenylosuccinate Lyase Adsl Asl Adenylosuccinase Asase |
Database Links | Reactome: R-HSA-73817 |
Alternative Antibody Names | Anti-Adenylosuccinate Lyase antibody Anti-Adsl antibody Anti-Asl antibody Anti-Adenylosuccinase antibody Anti-Asase antibody Anti-ADSL antibody Anti-AMPS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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