产品详情
简单介绍:
Anti-AFP antibody (395-609) (STJ119158)
详情介绍:
| Host: | Rabbit |
| Applications: | WB/IF/IP |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-AFP (395-609) is suitable for use in Western Blot, Immunofluorescence and Immunoprecipitation research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 IF/ICC 1:50-1:200 IP 1:50-1:100 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AFP |
| Gene ID: | 174 |
| Uniprot ID: | FETA_HUMAN |
| Immunogen Region: | 395-609 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 395-609 of Alpha-Fetoprotein (AFP) (NP_001125.1). |
| Immunogen Sequence: | DKGEEELQKYIQESQALAKR SCGLFQKLGEYYLQNAFLVA YTKKAPQLTSSELMAITRKM AATAATCCQLSEDKLLACGE GAADIIIGHLCIRHEMTPVN PGVGQCCTSSYANRRPCFSS LVVDETYVPPAFSDDKFIFH KDLCQAQGVALQTMKQEFLI NLVKQKPQITEEQLEAVIAD FSGLLEKCCQGQEQEVCFAE EGQKLISKTRAALGV |
| Tissue Specificity | Plasma. Synthesized by the fetal liver and yolk sac. |
| Post Translational Modifications | Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence. Sulfated. |
| Function | Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. |
| Protein Name | Alpha-Fetoprotein Alpha-1-Fetoprotein Alpha-Fetoglobulin |
| Database Links | Reactome: R-HSA-381426 Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Alpha-Fetoprotein antibody Anti-Alpha-1-Fetoprotein antibody Anti-Alpha-Fetoglobulin antibody Anti-AFP antibody Anti-HPAFP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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