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  • 产品名称：Anti-AGO3 antibody (STJ190813)

  • 产品型号：STJ190813
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-AGO3 antibody (STJ190813)
详情介绍：
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Protein argonaute-3 is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
ELISA 1:5000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: AGO3
Gene ID: 192669
Uniprot ID: AGO3_HUMAN
Specificity: AGO3 Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from part of the human protein
Function Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (siRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent siRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. Possesses RNA slicer activity but only on select RNAs bearing 5'- and 3'-flanking sequences to the region of guide-target complementarity.
Protein Name Protein Argonaute-3
Argonaute3
Hago3
Argonaute Risc Catalytic Component 3
Eukaryotic Translation Initiation Factor 2c 3
Eif-2c 3
Eif2c 3
Database Links Reactome: R-HSA-1912408
Reactome: R-HSA-203927
Reactome: R-HSA-2559580
Reactome: R-HSA-2559585
Reactome: R-HSA-4086398
Reactome: R-HSA-426486
Reactome: R-HSA-426496
Reactome: R-HSA-5628897
Reactome: R-HSA-5687128
Reactome: R-HSA-8853884
Reactome: R-HSA-8934593
Reactome: R-HSA-8936459
Reactome: R-HSA-8943723
Reactome: R-HSA-8948700
Reactome: R-HSA-8986944
Reactome: R-HSA-9018519
Reactome: R-HSA-9022692
Reactome: R-HSA-9029569
Reactome: R-HSA-9759811
Reactome: R-HSA-9768778
Cellular Localisation Cytoplasm
P-Body
Alternative Antibody Names Anti-Protein Argonaute-3 antibody
Anti-Argonaute3 antibody
Anti-Hago3 antibody
Anti-Argonaute Risc Catalytic Component 3 antibody
Anti-Eukaryotic Translation Initiation Factor 2c 3 antibody
Anti-Eif-2c 3 antibody
Anti-Eif2c 3 antibody
Anti-AGO3 antibody
Anti-EIF2C3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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