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  • 产品名称：Anti-ADAMTS8 antibody (176-185) (STJ72187)

  • 产品型号：STJ72187-100
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ADAMTS8 antibody (176-185) (STJ72187)
详情介绍：
Host: Goat
Applications: Pep-ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-ADAMTS8 (176-185) is suitable for use in ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: ELISA-antibody detection limit dilution 1:4000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: ADAMTS8
Gene ID: 11095
Uniprot ID: ATS8_HUMAN
Immunogen Region: 176-185
Accession Number: NP_008968.4
Immunogen Sequence: RQERGDHQED
Post Translational Modifications The precursor is cleaved by a furin endopeptidase. Glycosylated. Can be O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X(2)-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of ADAMTS family members. Can also be C-glycosylated with one or two mannose molecules on tryptophan residues within the consensus sequence W-X-X-W of the TPRs, and N-glycosylated. These other glycosylations can also facilitate secretion.
Function Has anti-angiogenic properties.
Protein Name A Disintegrin And Metalloproteinase With Thrombospondin Motifs 8
Adam-Ts 8
Adam-Ts8
Adamts-8
Meth-2
Meth-8
Database Links Reactome: R-HSA-1474228
Reactome: R-HSA-5083635
Reactome: R-HSA-5173214
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Antibody Names Anti-A Disintegrin And Metalloproteinase With Thrombospondin Motifs 8 antibody
Anti-Adam-Ts 8 antibody
Anti-Adam-Ts8 antibody
Anti-Adamts-8 antibody
Anti-Meth-2 antibody
Anti-Meth-8 antibody
Anti-ADAMTS8 antibody
Anti-METH2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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