产品详情
简单介绍:
Human ADAM12 (A Disintegrin And Metalloprotease 12) Sandwich ELISA Kit Ready-To-Use (STJE0013262)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 28pg/mL |
Detection Limit: | 78.1-5000pg/mL |
Short Description: | This ADAM12 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | ADAM12 |
Gene ID: | 8038 |
Uniprot ID: | ADA12_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
Tissue Specificity | Isoform 1 is expressed in placenta and skeletal, cardiac, and smooth muscle. Isoform 2 seems to be expressed only in placenta or in embryo and fetus. Both forms were expressed in some tumor cells lines. Not detected in brain, lung, liver, kidney or pancreas. |
Post Translational Modifications | The precursor is cleaved by a furin endopeptidase. |
Function | Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors. |
Protein Name | Disintegrin And Metalloproteinase Domain-Containing Protein 12 Adam 12 Meltrin-Alpha |
Database Links | Reactome: R-HSA-177929 Reactome: R-HSA-8941237 |
Cellular Localisation | Isoform 1: Cell Membrane Single-Pass Type I Membrane Protein Isoform 2: Secreted Isoform 3: Secreted Isoform 4: Secreted |
Alternative ELISA Names | Disintegrin And Metalloproteinase Domain-Containing Protein 12 ELISA kit Adam 12 ELISA kit Meltrin-Alpha ELISA kit ADAM12 ELISA kit MLTN ELISA kit UNQ346 ELISA kit PRO545 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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