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  • 产品名称：Human IL-22RA2/IL22BP protein (Recombinant) (C-His) (STJP000965)

  • 产品型号：STJP000965
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human IL-22RA2/IL22BP protein (Recombinant) (C-His) (STJP000965)
详情介绍：
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human IL-22RA2/IL22BP-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4. Contact us for customized product form or formulation.
Immunoreactivity: Measured by its binding ability in a functional ELISA. Immobilized recombinant Human IL22 at 2 Mu g/mL (100 Mu L/well) can bind recombinant Human IL22BP, the EC50 of Human IL22BP is 10.78 ng/mL.
Gene Symbol: IL22RA2
Gene ID: 116379
Uniprot ID: I22R2_HUMAN
Immunogen: Recombinant Human IL-22RA2/IL22BP Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Thr22-Pro231) of human IL-22BP/IL-22RA2 (Accession #NP_851826.1) fused with a 6×His tag at the C-terminus.
Tissue Specificity Expressed in placenta, spleen, breast, skin and lung. Also detected in intestinal tract, testis, brain, heart and thymus. No expression found in prostate, bladder, kidney, ovary, muscle, bone marrow, liver and uterus. Isoform 1 is expressed only in placenta. Isoform 2 is expressed in placenta and breast and at lower level in spleen, skin, thymus and stomach.
Function Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses. Isoform 1 may play a role in establishing and maintaining successful pregnancy.
Protein Name Interleukin-22 Receptor Subunit Alpha-2
Il-22 Receptor Subunit Alpha-2
Il-22r-Alpha-2
Il-22ra2
Cytokine Receptor Class-Ii Member 10
Cytokine Receptor Family 2 Member 10
Crf2-10
Cytokine Receptor Family Type 2 - Soluble 1
Crf2-S1
Interleukin-22-Binding Protein
Il-22bp
Il22bp
Zcytor16
Database Links Reactome: R-HSA-8854691
Cellular Localisation Secreted
Alternative Protein Names Interleukin-22 Receptor Subunit Alpha-2 protein
Il-22 Receptor Subunit Alpha-2 protein
Il-22r-Alpha-2 protein
Il-22ra2 protein
Cytokine Receptor Class-Ii Member 10 protein
Cytokine Receptor Family 2 Member 10 protein
Crf2-10 protein
Cytokine Receptor Family Type 2 - Soluble 1 protein
Crf2-S1 protein
Interleukin-22-Binding Protein protein
Il-22bp protein
Il22bp protein
Zcytor16 protein
IL22RA2 protein
UNQ5793 protein
PRO19598 protein
PRO19822 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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