产品详情
简单介绍:
Human Jagged1/JAG1/CD339 protein (Recombinant) (C-hFc) (STJP002673)
详情介绍:
Host: | HEK293 cells |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human Jagged1/JAG1/CD339-C-hFc protein was developed from hek293 cells and has a target region of C-hFc. For use in research applications. |
Formulation: | Lyophilized from a 0.2 Mu m filtered solution of PBS, pH7.4. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | JAG1 |
Gene ID: | 182 |
Uniprot ID: | JAG1_HUMAN |
Immunogen Region: | Trp896-Arg1065 |
Immunogen: | Recombinant Human Jagged1/JAG1/CD339 Protein is produced by Human cells expression system. The target protein is expressed with sequence (Trp896-Arg1065) of human Jagged-1/JAG1 (Accession #P78504) fused with an Fc tag at the C-terminus. |
Function | Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). |
Protein Name | Protein Jagged-1 Jagged1 Hj1 Cd Antigen Cd339 |
Database Links | Reactome: R-HSA-2122948 Reactome: R-HSA-2644606 Reactome: R-HSA-2660826 Reactome: R-HSA-2691232 Reactome: R-HSA-2894862 Reactome: R-HSA-2979096 Reactome: R-HSA-8941856 Reactome: R-HSA-9013149 Reactome: R-HSA-9013423 Reactome: R-HSA-9013507 Reactome: R-HSA-9013700 |
Cellular Localisation | Membrane Single-Pass Type I Membrane Protein Cell Membrane |
Alternative Protein Names | Protein Jagged-1 protein Jagged1 protein Hj1 protein Cd Antigen Cd339 protein JAG1 protein JAGL1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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