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  • 产品名称：Anti-AKR1B10 antibody (1-316) (STJ110133)

  • 产品型号：STJ110133
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-AKR1B10 antibody (1-316) (STJ110133)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-AKR1B10 (1-316) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: AKR1B10
Gene ID: 57016
Uniprot ID: AK1BA_HUMAN
Immunogen Region: 1-316
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-316 of human AKR1B10 (NP_064695.3).
Immunogen Sequence: MATFVELSTKAKMPIVGLGT WKSPLGKVKEAVKVAIDAGY RHIDCAYVYQNEHEVGEAIQ EKIQEKAVKREDLFIVSKLW PTFFERPLVRKAFEKTLKDL KLSYLDVYLIHWPQGFKSGD DLFPKDDKGNAIGGKATFLD AWEAMEELVDEGLVKALGVS NFSHFQIEKLLNKPGLKYKP VTNQVECHPYLTQEKLIQYC HSKGITVTAYSPLGSPDRPW AKPEDPSLLEDPKIKEIAA
Tissue Specificity Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.
Function Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays strong enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal. Plays a critical role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls). Displays no reductase activity towards glucose.
Protein Name Aldo-Keto Reductase Family 1 Member B10
Arl-1
Aldose Reductase-Like
Aldose Reductase-Related Protein
Arp
Harp
Small Intestine Reductase
Si Reductase
Database Links Reactome: R-HSA-975634
Cellular Localisation Lysosome
Secreted
Secreted Through A Lysosome-Mediated Non-Classical Pathway
Alternative Antibody Names Anti-Aldo-Keto Reductase Family 1 Member B10 antibody
Anti-Arl-1 antibody
Anti-Aldose Reductase-Like antibody
Anti-Aldose Reductase-Related Protein antibody
Anti-Arp antibody
Anti-Harp antibody
Anti-Small Intestine Reductase antibody
Anti-Si Reductase antibody
Anti-AKR1B10 antibody
Anti-AKR1B11 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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