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  • 产品名称：Human KRAS WT (HLA-A*03:01) Tetramer protein (Recombinant) (C-His & Avi) (STJP002360)

  • 产品型号：STJP002360-100
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human KRAS WT (HLA-A*03:01) Tetramer protein (Recombinant) (C-His & Avi) (STJP002360)
详情介绍：
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human KRAS WT (HLA-A*03:01) Tetramer-C-His & Avi protein was developed from hek293 cells and has a target region of C-His & Avi. For use in research applications.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Endotoxin: Less than 1EU per Mu g by the LAL method.
Gene Symbol: B2M
Gene ID: 567
Uniprot ID: B2MG_HUMAN
Immunogen Region: Gly25-Thr305 (HLA-A*03:01) , Ile21-Met119 (B2M) and VVVGAGGVGK
Immunogen: Recombinant Human KRAS WT (HLA-A*03:01) Tetramer Protein is expressed from Expi293 with His tag and Avi tag at the C-terminal, tetramer is assembled by biotinylated monomer and streptavidin.；It contains Gly25-Thr305 (HLA-A*03:01) , Ile21-Met119 (B2M)
Function Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation.
Protein Name Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3
Database Links Reactome: R-HSA-1236974
Reactome: R-HSA-1236977
Reactome: R-HSA-164940
Reactome: R-HSA-198933
Reactome: R-HSA-2172127
Reactome: R-HSA-2424491
Reactome: R-HSA-6798695
Reactome: R-HSA-877300
Reactome: R-HSA-9637628
Reactome: R-HSA-9705671
Reactome: R-HSA-977225
Reactome: R-HSA-983170
Cellular Localisation Secreted
Cell Surface
Detected In Serum And Urine
(Microbial Infection) In The Presence Of M
Tuberculosis Esxa-Esxb Complex Decreased Amounts Of B2m Are Found On The Cell Surface
Alternative Protein Names Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3 protein
B2M protein
CDABP0092 protein
HDCMA22P protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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