产品详情
简单介绍:
Human L-Selectin (CD62L) protein (Recombinant) (STJP000423)
详情介绍:
Host: | HEK293 |
Note: | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Recombinant-Human L-Selectin (CD62L)-protein was developed from hek293. For use in research applications. |
Conjugation: | Unconjugated |
Formulation: | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
Storage Instruction: | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
Endotoxin: | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
Immunoreactivity: | The activity was tested by the ability of immobilized recombinant human L-Selectin to bind Human CD34 NA |
Gene Symbol: | SELL |
Gene ID: | 6402 |
Uniprot ID: | LYAM1_HUMAN |
Immunogen Region: | ECD |
Immunogen: | Optimized DNA sequence encoding extracellular domain of Human L-Selectin including a C-terminal His tag was expressed in HEK293 cells. NA |
Tissue Specificity | Expressed in B-cell lines and T-lymphocytes. |
Post Translational Modifications | N-glycosylated. |
Function | Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. |
Protein Name | L-Selectin Cd62 Antigen-Like Family Member L Leukocyte Adhesion Molecule 1 Lam-1 Leukocyte Surface Antigen Leu-8 Leukocyte-Endothelial Cell Adhesion Molecule 1 Lecam1 Lymph Node Homing Receptor Tq1 Gp90-Mel Cd Antigen Cd62l |
Database Links | Reactome: R-HSA-198933 Reactome: R-HSA-202733 Reactome: R-HSA-6798695 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative Protein Names | L-Selectin protein Cd62 Antigen-Like Family Member L protein Leukocyte Adhesion Molecule 1 protein Lam-1 protein Leukocyte Surface Antigen Leu-8 protein Leukocyte-Endothelial Cell Adhesion Molecule 1 protein Lecam1 protein Lymph Node Homing Receptor protein Tq1 protein Gp90-Mel protein Cd Antigen Cd62l protein SELL protein LNHR protein LYAM1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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